The HCG Diet Information

Position paper on HCG injections Along with a very low calorie diet for weight loss The “HCG Diet has become popular in recent years due to Internet accessibility and advertising of clinics that perform the protocol. I have read ATW Simeons protocol “kilos and centimeters: a new approach to obesity” several times. The document is interesting in terms of theories Simeons “about weight gain and the role of hypothalamic dysfunction in the prevention of weight loss. It is also in bold – Simeons states that the protocol is easy to follow uniformly and effective at suppressing appetite, mood elevation, and allows “abnormal,” stubborn fat to lose. HCG also asserts that the hypothalamus is reset to prevent weight loss to be recovered. “Pounds and Inches” is available from several sources on the Internet. If you are interested, you can request a paper copy of Simeons’ describing his protocol published in 1954 in the journal The Lancet. (1) HCG or human chorionic gonadotropin is a hormone produced during pregnancy. It is also produced by tumors in women (hydatidiform mole) and men (testicular cancer). HCG Injections medically used as part of its molecular structure mimics luteinizing hormone (LH). HCG injections (in doses ranging from 1000 to 2000 units, 2-3 times per week) are used to increase testosterone production in men with low testosterone levels who want to preserve fertility. HCG injections (5,000 to 10,000 units) are sometimes used in women to induce ovulation. Simeons protocol uses minute doses HCG (125 units), 6-7 days per week for 23 to 40 days, along with a very low calorie (VLC) diet of 500 calories per day. Since HCG not share some of its molecular structure and the LH-stimulating hormone (TSH), in theory, can increase testosterone production, ovulation and progesterone production or release of thyroid hormone. It can also cause overstimulation of ovarian cysts and ovarian cancer. However The dose used is very small and these effects are unlikely. VLC diet (with or without HCG) may precipitate gallstones (as it is low in fat) and can cause symptoms of toxicity (as toxins fat stores). Research HCG injections and weight loss is almost entirely negative. In other words, most of the trials in the which patients received HCG injections or placebo and followed identical diets VLC, show no difference in the amount of weight loss, the rate of weight loss, hunger level, or mood. A summary of published studies is this paper. I’ve read no study has looked at the long-term maintenance of weight loss with HCG protocol. Randomized controlled trials of VLC diets show a wide variation in the initial percentage of regain lost weight. Participants in these trials retrieved 7-122% of initial weight lost for a year, and 26-121% in 5 years. (2) Active monitoring of weight maintenance programs that include behavioral therapy, nutrition education, and exercise are more effective in improving weight maintenance. It would be worthwhile to conduct a clinical trial to see if participants following the protocol of HCG have more successful at maintaining weight loss than diet alone VLC. Simeons patient claims that follow its Protocol to maintain weight loss of 60-70% of the time, although I do not believe that published data to support this assertion. I’ve talked to many patients who have followed the protocol of HCG with great success – they have lost much weight, not feeling hungry, and had a greater sense of wellbeing. Many of these people have lost weight ., I have personally gone through the Simeons protocol, documentation of all calories consumed and calories burned (to use a Bodybugg ®). I also measured my fat percentage and muscle before and after the diet by analyzing impedance impedance. I lost 12 pounds and 4% body fat in the protocol of 23 days. I was very hungry people throughout the entire protocol, but I did exercise every day. Some advocates of the protocol recommends not exercising, but this seems a bad advice, given the overwhelming health benefits of regular exercise. My position on the protocol of HCG for weight loss is that I do not think it’s harmful. Nor do I believe having no effect over placebo. I do not discount the power of any placebo. The placebo response is really a measure of the power of self-healing ability. I believe that should be informed about research on HCG and weight loss before you undergo this protocol. Also make sure your doctor is aware of his current health condition before following any diet VLC, and that the causes of abnormal weight gain (eg, hypothyroidism, hypogonadism, and other endocrine problems) were discarded. Before entering into any diet VLC, I’d recommend also undergone a detoxification program that supports Phase I and Phase II liver function. Make sure you do not have pre-existing gallstones, or liver or kidney. If using insulin to manage diabetes, you should make sure the dose is adjusted based on blood sugar levels blood, and do not develop ketoacidosis, which can be fatal. Note that since 1975, the FDA requires the following information to be provided with any advertising or promotion HCG loss Weight: HCG has not proven effective adjuvant therapy in the treatment of obesity. There is substantial evidence that it increases weight loss beyond that resulting from caloric restriction, resulting in more attractive or “normal” distribution of fat, or reduced hunger and discomfort associated with calorie diets. Dr. Kathryn Retzler AT Simeons 1. Action of chorionic gonadotropin in the obese. Lancet. 1954 6 November, 267 (6845) :946-7. 2 Saris W. Very low calorie diets and sustained weight loss. Obesity Research. 2001, Suppl 4:295 S-301S. 3 Lukaczer D, Liska D, Lerman R, et al. Effect of a low glycemic index diet with soy protein and phytosterols in cardiovascular risk factors in postmenopausal women. Nutrition 2006, 22:104-113. Summary < ; strong> Research and Articles RE: HCG injections & ; VLC Diet weight loss Note: Dr. Simeons HCG not only indicates that the weight loss achieved, but claims for patients treated with HCG never be hungry or tired, going to lose a different kind of weight ( “abnormal fat” that is hard to lose), and experience a greater sense of well being. It also says that weight loss is unlikely to be recovered ( “60-70%” of patients to alleviate the weight) due to an adjustment of the hypothalamus. positive studies: < ; / p> Asher W, Harper H. Effect of human chorionic gonadotropin in weight loss, hunger, and sense of wellbeing. Am J Clin Nutr. 1973, 26 (2) :211-8. This study is a well-designed, randomized, double-blind 40 women who received placebo or hCG treatment in a clinic with hCG (Harold Harper, MD). All followed a diet 500 to 550 kcal, 20 received 125 IU of hCG, six days a week for 6 weeks (36 injections), 20 received injections of placebo six days a week (36 shots). The average age group of HCG was 37. 8; placebo group 38. 4 years. Results: Mean weight loss (HCG: 19. 96 + / – 1. £ 63, placebo: 11. 05 + / – 1. £ 29) and percentage of starting weight loss (HCG: 11. 47%, placebo: 6. 77%) was higher in the group hCG than the placebo group. Fourteen patients lost 15 pounds or more in the HCG group, 5 lost 15 pounds or more in the placebo group. hunger was reduced (HCG: 76. 6% of respondents indicated little or no daily hunger placebo group 48. 7% of respondents indicated little or no daily hunger). sensation of wellbeing is higher in the HCG (HCG: 86. 5 % said they felt “good” to “excellent”; placebo: 70% said they felt “good” to “excellent”). Blood pressure was not significantly different between the two groups. Interestingly, patients of Dr. Harper’s that received injections of placebo lost more weight than the average patient or HCG or placebo, 4 of other doctors. The authors concluded: “Therefore, HCG used in an informal program of weight reduction, as it is used to often in general practice, has no value “, which means that very low calorie diet is the critical element that leads to weight loss. Guzman H. chorionic gonadotropin in obesity. Other clinical observations. Am J Clin Nutr . 1969; 22:686. < p> In this article, Dr. Guzman said that is treated “more than 2,500 patients of both sexes, aged between 15 and 75″ with the protocol Simeons’ HCG. Guzmán studied with ATW Simeons clinic in Rome. This Article Simeons analyzes the concept of obesity, namely, a “definite metabolic disorder, much as diabetes is caused by an interruption of a regulatory mechanism located in the. Hypothalamus … “We call this” fat regulation center. “ Guzmán explains that fat cells in the obese differ from normal in the fat cells are more numerous and larger. These “heavy” fat cells metabolize glucose less efficiently than normal fat cells. normal adipose tissue has two functions: building materials (to protect organs and blood vessels) and storage of fuel. abnormal fat tissue is also a potential reservoir for fuel, but is not immediately available for emergency nutrition. Only after the normal fat reserves are depleted that the use of abnormal body fat. Restriction severe calories leads to depletion of fat reserves earlier than normal abnormal fat is used, and the patient will be weak and hungry “, while ugly fat deposits – of which originally wanted to get rid – just been reduced. At this point, the patient often becomes depressed and frustrated, and diet is abandoned. “ The only type of” nutritional emergency “, where all types of fat cells are immediately usable during pregnancy. Simeons HCG suggests that produces changes in hypothalamic obesity prevention during pregnancy. Gusman records collected from 450 patients who received 3 or 6 weeks of treatment. He does the following observations: 1) 90% of patients were able to reduce their weight , 2) 60-70% achieved its desired normal weight, 3) “most”, said the regiment was the easiest and most successful to follow, 4) “many” who recovered all or part of their weight they have to maintain their weight as before, and did not care to return for treatment, 5) “most patients” experienced “high” despite the marked low food intake, and 6) the notable obese were the most satisfactory results. Lebon P. Treatment of overweight patients with chorionic gonadotropin. J Am Geriatr Soc 1966 , 14:116. Lebon P. Action of chorionic gonadotropin in the obese. Lancet. 1961, 2:268. AT Simeons . The action of chorionic gonadotropin in the obese. Lancet. 1954 6 November, 267 (6845) :946-7. Stuart C. gonadotophin action Chorionic in the obese. Lancet. 1961, 278 (7196) :268-9. negative studies:

Bosch B, Venter I, Stewart RI, et al. human chorionic gonadotropin and weight loss. A double-blind, placebo-controlled trial. S Afr Med J. 1990, 77 (4) :185-9. This study was a double-blind, placebo-controlled study were compared with placebo injections of HCG for weight loss. Forty obese women (body mass index above 30 kg/m2) were placed on the same diet supplying 5,000 kJ per day and received daily intramuscular injections of saline or HCG, 6 days a week for 6 weeks. A psychological profile, the level of hunger, body circumference, a fasting blood sample and food records obtained at the beginning and end of the study, whereas body weight was measured weekly. Results: Subjects receiving HCG injections showed no advantages over those of placebo on any of the recorded variables. In addition, weight loss diet was similar to severely restricted intake. The authors conclude: “There is no justification for the use of HCG injections in the treatment of obesity.” Craig L, Ray R, S Waxler, et al. chorionic gonadotropin in the treatment of obese women. Am J Clin Nutr. 1963, 12:230-234. < ; / strong> diet study was double-blind, placebo-controlled study to evaluate the effectiveness of the method of Simeon using HCG versus placebo, and 550 calories per day. Twenty obese women were treated for forty days. Results: all subjects, but weight loss, but losses were small and not uniform, suggesting adherence to the diet varied. The basal metabolic rate increased in four subjects HCG and two control subjects. Greenway FL, Bray GA. Gonadotrohpin human chorionic (hCG) in the treatment of obesity: a critical assessment of the Simeons method. West J Med 1977, 127 (6), 461-3. This study was a double-blind, placebo-controlled trial using injections HCG or placebo to evaluate weight loss, the level of hunger, mood, and localized (in situ), while the reduction of a diet low in calories. Results: The weight loss was identical between the two groups , and there was no evidence of differential effects on hunger, mood or body measurements found. The authors conclude that “placebo injections, therefore, seem to be as effective as HCG in the treatment of obesity . Lijesen S, Theeuwes I, Assendelft W, et al. The effect of the hormone human chorionic gonadotropin (HCG) in the treatment of obesity through the Simeons therapy : a criteria-based meta-analysis. Br J Clin Pharmacol 1995, 40:237-243.

This paper was a meta-analysis of eight uncontrolled and 16 randomized controlled to measure the effect of HCG in the treatment of obesity. The tests are scored on the quality and methods (based on four main categories: population study, interventions, effect measurement and data reporting and analysis) and the main conclusion of the author (s) for weight loss, fat redistribution, hunger and sense of wellbeing. Results methodological ranged from 16 to 73 points (maximum score 100), suggesting that most studies were of poor methodological quality. Of the 12 studies scoring 50 or more points, one reported that HCG is a useful adjunct . Studies of adding 50 or more points were controlled. The authors concluded: “there is no scientific evidence that HCG is effective in treating obesity, which carries no weight loss or fat redistribution, nor reduce hunger or induce a feeling of comfort. “ Miller R, Schneiderman LJ. A clinical study on the use of human chorionic gonadotropin in weight reduction. ; J Fam Pract 1977 Mar; 4 (3) :554-8. obesity treatment with the gonadotropin human chorionic has proved of no more value than saline in a double-blind crossover study of weight reduction in obese individuals. There were no significant differences in mood, hunger, or shots missed, and no difference apparent adherence to the diet when comparing the two agents. By contrast, a significant difference was found in the subjects’ ability to lose weight in the first four weeks of the study, in contrast to the second of four weeks, no matter that a product is used. Thus, the beginning of a new treatment program, including through an inert agent, has a temporary benefit – a manifestation of both placebo effect and the Hawthorne effect. < ; strong> T Rabe, Richter S, L Kiesel, B Runnebaum [risk-benefit analysis of hCG-500 kcal reduction diet (Roman priest) in women]. Geburtshilfe Frauenheilkd. May 1987, 47 (5) :297-307. The British physician ATW Simeons described in 1954 a new method of dieting. are combined with a reduction diet (500 kcal per day) with daily injections of the hormone human chorionic gonadotropin (hCG) (IM 125 IU). According Simeons the patient should not lose more weight during the 4-a 6-week-diet without hCG, but the injections should facilitate to maintain the diet and lose weight in certain parts of the body (eg hip, belly, thigh). After the publication of the first studies performed with different male and female patients analyzed the effectiveness of Roman “cures.” 10 of these studies showed positive and another 10 studies negative results with respect to the hCG-related weight loss. Two of these studies with positive results were double-blind (hCG vs. placebo). Most of them were reports on therapeutic experiences and uncontrolled. According to these reports, the body proportions normalized and the feeling of hunger was tolerable. Four out of 10 studies with negative results were controlled studies ( hCG vs. control without hCG), whereas 6 were double-blind studies. These studies showed a significant weight reduction during dieting, but no differences between treatment groups in relation to body weight, body proportions and feel hunger. One of them is the only German study conducted by Rabe et al. in 1981, in which injections of 82 premenopausal volunteers had been randomized hCG diet either with or without hCG. In recent publications that describe in their most well documented double-blind studies authors largely reject hCG administration in the diet. Supporters of the hCG diet must prove the effectiveness of this method in controlled studies according to the German law on drugs. Until then the opinion of the German panel steroid toxicology remains valid, that hCG is ineffective in the diet and should not be used. Shetty KR, Kalkhoff RK. Human chorionic gonadotropin (HCG) treatment of obesity. Arch Intern Med 1977 Feb; 137 (2) :151-5. < / p> This study compared after a period of nine days of monitoring, six hospitalized obese women given 125 IU of human chorionic gonadotropin (HCG) intramuscularly daily for 30 days with five obese women who received injections of diluent only (placebo. patients consumed identical diets of 500 calories per day for the same period. Although the number of patients was small, the study is significant because the diets of patients and all injections were monitored closely in a hospital setting. Results: Mean weight loss in the HCG-treated group was almost identical to skinfold obtained by women who received placebo. Reduction of body measurements of the triceps or chest circumference, waist, hips, thighs, not were different. Patterns of change in a variety of substrates from plasma and urine, electrolytes, hormones and are similar in both groups and consistent with starvation and weight loss. The authors concluded: “These results indicate that HCG has no effects on chemical and hormonal parameters measured and offers no advantage over calorie restriction in promoting weight loss. “ Stein MR, Julis RE, Peck CC, et al. Ineffective e SS of human chorionic gonadotropin in weight reduction: a double blind study. Am J Clin Nutr. 1976, 29 (0) :940-8. This was a well-designed, randomized, double blind 51 women who received HCG or placebo for 32 days (28 injections), with 500 to 550 kcal / day diet. The study was designed to duplicate the study Asher Harper (above). Each patient received the same diet (established in Asher study Harper), was weighed daily Monday through Saturday and was advised by one of the researchers administering the injections. Results: There were no statistically significant differences in the means of the two groups in the number of injections received, loss weight (HCG: 15. £ 79, placebo: 15. £ 52) per cent weight loss (HCG: 9. 48%, placebo: 9. 25%), hip and waist circumference, loss of weight by injections or hunger rates. The authors concluded: “HCG does not improve the efficacy of a rigidly imposed regimen for weight reduction.” Young RL, Fuchs RJ, MJ Woltjen. chorionic gonadotropin in weight control. A study double-blind crossover. JAMA. 1976, 236 (22): 2495. Two hundred two patients participated in a double-blind, randomized, crossover, the effectiveness of human chorionic gonadotropin (HCG) versus placebo in reduction program weight. Measurements were powerful number, thickness of skin fold, dropout rates, reasons for dropout, and the patient’s subjective response. Results: No statistically significant difference between those receiving HCG versus placebo during any phase of this study. Other interesting studies < / p> Sohar E. A forty days 550 calories in the treatment of obese outpatients. Am J Clin Nutr. ; 1959, 7:514-518. The purpose of this study was to present a method to produce rapid weight loss in obese patients. This study looked at forty – five patients who started courses fifty-three 550 calories, consisting of two meals in detail. Patients were told what to eat (diet Simeon) and were not told in calories. Thirty-nine patients received injections of HCG (125 units ), fourteen received daily injections of saline. Patients were told that weight reduction is due to diet, but the injections help to decrease the appetite. The authors assumed from the outset that the HCG was ineffective in terms of weight reduction. Injections were given for “psychological reasons only” because patients were assured that would curb the appetite. The authors claim that the prescribed diet is a success Simeon because the daily average weight loss is high due to very low calories. Patients are more likely to stick to the diet, due to time constraints – I. e., they know that diet only last 40 days. claim “The vast majority of patients are willing to suffer for the forty days of the award of loss than expected and the possible amount of 20 pounds.” The author also conjectures that the success is due to the fact that food prescribed, not calories. This eliminates the estimate that usually continues to counting calories. In other words, most patients do not weigh or measure foods and not calories are not burned correctly. Sohar recommends advising patients not in terms of calories, but to prescribe in detail the meals. Another reason given for the Sohar

Diet Success is down only two meals per day, therefore, contact with food is minimal. Finally, the activity level is free “, which allows all obese people, are mostly housewives, to reduce.” Sohar points your paper and the work of Simeon, shows that obese patients can lead normal lives who work moderate at 500 to 600 calories per day. (1) AT Simeons . The action of chorionic gonadotropin in the obese. Lancet. 1954 6 November, 267 (6845) :946-7. (2) Lukaczer D, Liska D, Lerman R, et al . Effect of a low glycemic index diet with soy protein and phytosterols on cardiovascular risk factors in postmenopausal women. Nutrition 2006, 22:104-113.

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